Scyllo-inositol prevents amyloid aggregation in mice

Certain variants of a simple sugar ameliorate Alzheimer's-like disease in mice, according to a new study by Canadian researchers. Although the new studies are still in the early stages, the findings could lead to new therapies that prevent or delay the onset of Alzheimer's disease.

The new studies show that some types of a sugar called cyclohexanehexol—also known as inositol—prevented the accumulation of amyloid β deposits, a hallmark of Alzheimer's disease. Scyllo-inositol treatment also improved cognitive abilities in the mice and allowed them to live a normal lifetime. The study appeared in advance online publication of the journal Nature Medicine on June 11, 2006.

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